Most commonly prescribed benzodiazepines for anxiety and sleeping that you can buy online: Alprazolam, Clonazepam, Diazepam.
Benzodiazepines are a group of chemically similar, psychoactive drugs for the treatment of nervous system overexcitation, rapid sedation and sleep. Benzodiazepines produce Gamma Aminobutyric Acid – “brake-fluid”, which suppresses nerve impulses and reduces activity. After taking benzodiazepines, you’ll feel calmer and sleepy.
The most common disorders treated with benzodiazepines are insomnia, anxiety, aggression, depression, phobias, and panic attacks. Depending on the specific disorder and dosage, benzodiazepines can quickly relieve symptoms and, together with other treatments, bring the patient back to normal.
For example, benzodiazepines are good treatments for irritability and fatigue. Weaknesses, intolerance to the environment, impatience are reduced, and in general, the behavior is streamlined. Due to the general sedation from benzodiazepines, the night sleep sets in faster.
Benzodiazepines are also effective against obsessions and phobias, in the case of constant doubts, indecision, anxious suspiciousness, and feelings of inadequacy. If these states do not disappear completely, then they at least fade after taking the medication, without the previous emotional saturation.
How do benzodiazepines work
In the USSR, they conducted a series of experiments on rats under stress, which showed how benzodiazepines can make people more confident and social.
In the first case, the rat was placed in a box containing a metal cup with water, to which an electric current is connected. As soon as the rat started drinking water, a current was turned on; which hit the rat, forcing it to move away from the cup, after the introduction of benzodiazepine, the rat drunk water, despite the painful electric shocks. Benzodiazepines stimulate courage to the point that they would allow you to survive, despite danger.
In the second experiment, two rats were placed in a box with an “electric floor”, the escape from which was a single wooden chair. Without medicine, the rats fought each other for a safe place, after taking benzodiazepine – the rats figured out that there was enough space in the chair for two. Benzodiazepines developed social tolerance and friendliness.
In a third experiment, a rat was trained to find its way to food in a dark, unfamiliar maze, under conditions of light stress. Usually a rat finds its way without any problems using his sense of smell, but as soon as the spotlight starts blinking strongly, the rat loses its ability to navigate in space from excitement. After taking benzodiazepine, the rat was no longer afraid of light and found food in the maze, even when the searchlight blinks. Benzodiazepines help ignore strong stimuli when there is a more important target.
Types of benzodiazepines
Considering how long it takes for it to leave our system, benzodiazepines are divided into drugs with a short and long period of action. For short-acting substances, this period is 2 to 6 hours. The long-term ones include benzodiazepines with a half-life of 20 to 150 hours.
Short-acting benzodiazepines such as Alprazolam and Lorazepam have a high risk of addiction because the drug wearing off quickly often leads to withdrawal symptoms. During this time, the symptoms for which it was prescribed may return.
For example, in some patients with panic disorder taking Alprazolam, in between doses, relapses of anxiety may occur, which can cause them to increase the frequency of taking the pills up to 4-5 times a day. In patients taking Lorazepam to treat insomnia, symptoms may present with early awakening or anxiety.
The problem can be solved by switching the patient to a long-acting benzodiazepine. For example, when treating chronic anxiety, it makes sense to change Alprazolam to Clonazepam. In case of insomnia, Lorazepam is substituted for Diazepam. Long-term benzodiazepines are commonly prescribed for chronic anxiety disorders.
Today there are about 60 types of benzodiazepines. The new drugs are attempts by scientists to improve old versions, to deprive them of their previous shortcomings. For example, in addition to a feeling of calmness, improved benzodiazepines do not cause drowsiness the next day, they work faster and longer.